{"id":38,"date":"2015-08-13T16:10:49","date_gmt":"2015-08-13T16:10:49","guid":{"rendered":"http:\/\/44.196.76.129\/?page_id=38"},"modified":"2025-07-14T22:42:24","modified_gmt":"2025-07-14T22:42:24","slug":"research","status":"publish","type":"page","link":"https:\/\/morcoslaboratory.org\/?page_id=38","title":{"rendered":"Research"},"content":{"rendered":"<div id=\"pl-38\"  class=\"panel-layout\" ><div id=\"pg-38-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-38-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-38-0-0-0\" class=\"so-panel widget widget_black-studio-tinymce widget_black_studio_tinymce panel-first-child panel-last-child\" data-index=\"0\" ><div class=\"textwidget\"><p>Our\u00a0lab focuses on solving problems at the interface between biology, computation, mathematics and biophysics. The primary focus of the lab is the development and application of methods to extract biological information from sequence and genomic data in combination with physical models to study molecular evolutionary landscapes, biomolecular structure and function, macro-complex formation, specificity in biological networks and its applications to understand and fight disease.<\/p>\n<\/div><\/div><\/div><\/div><div id=\"pg-38-1\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-38-1-0\"  class=\"panel-grid-cell\" ><div id=\"panel-38-1-0-0\" class=\"widget_text so-panel widget widget_custom_html panel-first-child panel-last-child\" data-index=\"1\" ><div class=\"textwidget custom-html-widget\"><div style=\"display: grid; grid-template-columns:1fr 1fr 1fr; grid-template-areas: 'img1 img2 img3' 'text1 text2 text3'; column-gap:20px; margin-bottom: 10px;\">\n\t<div style=\"display:flex; justify-content:center;  align-items:center; grid-area:img1; margin-bottom: 30px;\">        \n\t\t<a href=\"https:\/\/morcoslaboratory.org\/?page_id=316\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/morcoslaboratory.org\/wp-content\/uploads\/2015\/08\/DCA-coevolution.jpg\" alt=\"Pdir\" style=\"width:auto; height:255px;\"\/>\n\t\t<\/a>\n\t<\/div>\n\t<div style=\"width:100%; display:flex; justify-content:center;  align-items:flex-start;grid-area:text1;\">\n\t\t<p style=\"text-align: center; \">\n\t\t\t<strong>Biomolecular Structure, <\/strong><strong>Function &amp; Design<\/strong>\n\t\t<\/p>\n\t<\/div>\n\t<div style=\"display:flex; justify-content:center; align-items:center; grid-area:img2; margin-bottom: 30px;\">        \n\t\t<a href=\"https:\/\/morcoslaboratory.org\/?page_id=325\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/morcoslaboratory.org\/wp-content\/uploads\/2025\/07\/Adobe-Express-file.png\" alt=\"\" style=\"width:auto; height:270px;\" \/>\n\t\t<\/a>\n\t<\/div>\n\t<div style=\"width:100%; display:flex; justify-content:center;  align-items:flex-start; grid-area:text2;\">\n\t\t<p style=\"text-align: center; \">\n\t\t\t<strong>Biomolecular\u00a0<\/strong><strong>Interactions &amp; Networks<\/strong>\n\t\t<\/p>\n<\/div>\n\t<div style=\"display:flex; justify-content:center; align-items:center; grid-area:img3; margin-bottom: 30px;\">        \n\t\t<a href=\"https:\/\/morcoslaboratory.org\/?page_id=295\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/morcoslaboratory.org\/wp-content\/uploads\/2015\/08\/Pdir.png\" alt=\"Pdir\" style=\"width:auto; height:130px;\" \/>\n\t\t<\/a>\n\t<\/div>\n\t<div style=\"width:100%; display:flex; justify-content:center;  align-items:flex-start; grid-area:text3;\">\n\t\t<p style=\"text-align: center; \">\n\t\t\t<strong>\n\t\t\t\tStatistical Inference,\u00a0Information Theory, Machine Learning &amp; Simulation\n\t\t\t<\/strong>\n\t\t<\/p>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><div id=\"pg-38-2\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-38-2-0\"  class=\"panel-grid-cell\" ><div id=\"panel-38-2-0-0\" class=\"widget_text so-panel widget widget_custom_html panel-first-child panel-last-child\" data-index=\"2\" ><div class=\"textwidget custom-html-widget\"><div style=\"display: grid; grid-template-columns:1fr 1fr 1fr; grid-template-areas: 'img1 img2 img3' 'text1 text2 text3'; column-gap:20px; margin-bottom: 10px;\">\n\t<div style=\"display:flex; justify-content:center;  align-items:center; grid-area:img1; margin-bottom: 30px;\">        \n\t\t<a href=\"https:\/\/morcoslaboratory.org\/?page_id=357\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/morcoslaboratory.org\/wp-content\/uploads\/2015\/08\/DISscore.png\" alt=\"\" style=\"width:auto; height:270px;\"\/>\n\t\t<\/a>\n\t<\/div>\n\t<div style=\"width:100%; display:flex; justify-content:center;  align-items:flex-start;grid-area:text1;\">\n\t\t<p style=\"text-align: center; \">\n\t\t\t<strong>Two Component \u00a0<\/strong><strong>Systems &amp; Molecular Specificity<\/strong>\n\t\t<\/p>\n\t<\/div>\n\t<div style=\"display:flex; justify-content:center; align-items:center; grid-area:img2; margin-bottom: 30px;\">        \n\t\t<a href=\"https:\/\/morcoslaboratory.org\/?page_id=370\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/morcoslaboratory.org\/wp-content\/uploads\/2025\/07\/SEEC-SF-Long-old.png\" alt=\"\" style=\"width:auto; height:230px;\" \/>\n\t\t<\/a>\n\t<\/div>\n\t<div style=\"width:100%; display:flex; justify-content:center;  align-items:flex-start; grid-area:text2;\">\n\t\t<p style=\"text-align: center; \">\n\t\t\t<strong>Molecular\u00a0<\/strong><strong>Evolution<\/strong>\n\t\t<\/p>\n<\/div>\n\t<div style=\"display:flex; justify-content:center; align-items:center; grid-area:img3; margin-bottom: 30px;\">        \n\t\t<a href=\"https:\/\/morcoslaboratory.org\/?page_id=373\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/morcoslaboratory.org\/wp-content\/uploads\/2015\/08\/Drug-Gene-Net.jpg\" alt=\"Pdir\" style=\"width:auto; height:200px;\" \/>\n\t\t<\/a>\n\t<\/div>\n\t<div style=\"width:100%; display:flex; justify-content:center;  align-items:flex-start; grid-area:text3;\">\n\t\t<p style=\"text-align: center; \">\n\t\t\t<strong>Biomedical \u00a0<\/strong><strong>Applications<\/strong>\n\t\t<\/p>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><div id=\"pg-38-3\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-38-3-0\"  class=\"panel-grid-cell\" ><div id=\"panel-38-3-0-0\" class=\"widget_text so-panel widget widget_custom_html panel-first-child panel-last-child\" data-index=\"3\" ><div class=\"textwidget custom-html-widget\"><div style=\"display: grid; grid-template-areas: 'img1' 'text1'; column-gap:20px; margin-bottom: 10px;\">\n\t<div style=\"display:flex; justify-content:center;  align-items:center; grid-area:img1; margin-bottom: 30px;\">        \n\t\t<a href=\"https:\/\/morcoslaboratory.org\/?page_id=385\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/morcoslaboratory.org\/wp-content\/uploads\/2025\/07\/Adobe-Express-file-2.png\" alt=\"\" style=\"width:auto; height:270px;\"\/>\n\t\t<\/a>\n\t<\/div>\n\t<div style=\"width:100%; display:flex; justify-content:center;  align-items:flex-start;grid-area:text1;\">\n\t\t<p style=\"text-align: center; \">\n\t\t\t<strong>Software Tools<\/strong>\n\t\t<\/p>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Our\u00a0lab focuses on solving problems at the interface between biology, computation, mathematics and biophysics. The primary focus of the lab is the development and application of methods to extract biological information from sequence and genomic data in combination with physical models to study molecular evolutionary landscapes, biomolecular structure and function, macro-complex formation, specificity in biological <a class=\"moretag\" href=\"https:\/\/morcoslaboratory.org\/?page_id=38\">Read More &#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"full-width-page.php","meta":{"footnotes":""},"class_list":["post-38","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/morcoslaboratory.org\/index.php?rest_route=\/wp\/v2\/pages\/38","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/morcoslaboratory.org\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/morcoslaboratory.org\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/morcoslaboratory.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/morcoslaboratory.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=38"}],"version-history":[{"count":268,"href":"https:\/\/morcoslaboratory.org\/index.php?rest_route=\/wp\/v2\/pages\/38\/revisions"}],"predecessor-version":[{"id":1792,"href":"https:\/\/morcoslaboratory.org\/index.php?rest_route=\/wp\/v2\/pages\/38\/revisions\/1792"}],"wp:attachment":[{"href":"https:\/\/morcoslaboratory.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=38"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}