Morcos Lab

Evolutionary Information Lab

Our lab focuses on solving problems at the interface between biology, computation, mathematics and biophysics. The primary focus of the lab is the development and application of methods to extract biological information from sequence and genomic data in combination with physical models to study molecular evolutionary landscapes, biomolecular structure and function, macro-complex formation, specificity in biological networks and its applications to understand and fight disease.

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jgi Joint Genome Institute @jgi ·
12 Aug

From our FY26 Functional Genomics call: Fluorine compounds resist biological breakdown — Sheel Dodani will use genomics, AI and lab tests to find and validate microbial defluorinase enzymes for biotech.

@MorcosLab @UTD_Biology @UTDResearch
Full portfolio: https://jointgeno.me/FGFY26

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morcoslab Morcos Lab @morcoslab ·
28 Aug

Our recent work that has been published in ACS central science. This is a collaboration with the labs of @MeloniLab & @hedi_65 Dr. Torabifard. We explored the landscape of non-extant proteins to generate a novel funcional multidomain ATPase copper transporters.

@ACSPublications

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morcoslab Morcos Lab @morcoslab ·
2 Jul 2025

Congratulation to Dr. Cheyenne Ziegler for successfully defending her Ph.D. thesis @UTD_Biology. I’m really proud of her accomplishments and excited for her next stage doing ML/Bio drug discovery!

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